Author

Mehul Makwana

John Innes Centre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Anna E. LindelliD· 1 shared Eneko VillanuevaiD· 1 shared Indra RouxiD· 1 shared Kathryn Susan LilleyiD· 1 shared Kiran Raosaheb PatiliD· 1 shared Kishor D. IngoleiD· 1 shared Nianshu ZhangiD· 1 shared Nonantzin Beristain CovarrubiasiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperSystems Biology

Anna E. LindellORCID

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1 paper

Recent·Most cited

Network-scale disruption of RNA-protein interactions by a bioaccumulating small-molecule drug

Xiaoteng Jiang, Simone Mozzachiodi, Indra Roux, Mehul Makwana, W Zhou, Eneko Villanueva, Stephan Kamrad, Anna E. Lindell, Nonantzin Beristain Covarrubias, Kishor D. Ingole, Nianshu Zhang, Sanjeeva Srivastava, Sonja Blasche, Kathryn Susan Lilley, Kiran Raosaheb Patil

This study shows that the antidepressant duloxetine disrupts RNA-protein interactions in both human and bacterial cells, revealing a new mechanism of drug action.

bioRxiv · Jul 24, 2026 · PreprintSystems Biology