Author

Mark van der Klok

University of GroningenORCID 0000-0002-2699-2285Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

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Erik Van der GiesseniD· 1 shared Maurice DekkeriD· 1 shared Patrick R. OnckiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperBiophysics

Erik Van der GiessenORCID

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1 paper

Recent·Most cited

BiophysicsJournal of Chemical Theory and ComputationPeer-reviewedAug 1, 2025

A coarse-grained MD model for disorder-to-order transitions in polyQ aggregation

Maurice Dekker, Mark van der Klok, Erik Van der Giessen, Patrick R. Onck

This study develops a coarse-grained MD model to study polyQ aggregation mechanisms and finds that longer sequences aggregate faster and amyloid growth occurs primarily in the β-sheet direction.

8 citations

protein structuremechanistic / dynamical model

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