Erik Van der Giessen

This study designs and tests artificial FG-Nups to show that spacing and charge-to-hydrophobicity ratio affect Kap95 binding and transport selectivity through NPCs.

This study presents a modeling framework simulating nuclear transport at full amino-acid resolution, revealing the dynamic FG-meshwork and role of Nsp1 and NTRs in transport.

This study develops a coarse-grained MD model to study polyQ aggregation mechanisms and finds that longer sequences aggregate faster and amyloid growth occurs primarily in the β-sheet direction.