Author

Michel van Kempen

Max Planck Institute for Multidisciplinary SciencesORCID 0000-0002-2720-5714Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:protein structure· 3 Research Focus:protein structure prediction· 3 Approach:statistical model· 3 Approach:deep learning· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Organism:multiple species· 1

Frequent Co-Authors

Johannes SödingiD· 3 shared Martin SteineggeriD· 3 shared Milot MirditaiD· 2 shared Cameron L. M. GilchristiD· 1 shared Charlotte TumescheitiD· 1 shared Gyuri KimiD· 1 shared Jeanne TrinquieriD· 1 shared Jeong-Jae LeeiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBioinformatics

Johannes SödingORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BioinformaticsbioRxivPreprintNov 24, 2025

LoL-align: sensitive and fast probabilistic protein structure alignment

Lasse Reifenrath, Michel van Kempen, Gyuri Kim…·Johannes Söding

LoL-align improves protein structure alignment by maximizing a local log-odds score, outperforming TMalign and DALI in sensitivity and speed.

1 citation

protein structurestatistical model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintMay 9, 2025

SoftAlign: End-to-end protein structures alignment

Jeanne Trinquier, Samantha Petti, Sukhwan Park…·Sergey Ovchinnikov

SoftAlign is an end-to-end protein structure alignment method that improves accuracy over existing tools while being compatible with other alignment strategies.

3 citations

protein structuredeep learning

𝕏 PostBluesky

BioinformaticsNature BiotechnologyPeer-reviewedMay 8, 2023

✦ In-depth digest

Foldseek: fast and accurate protein structure search

Michel van Kempen, Stephanie S. Kim, Charlotte Tumescheit…·Martin Steinegger

Foldseek's 3Di tertiary-interaction alphabet enables structure search four to five orders of magnitude faster than Dali and TM-align at 86% and 88% of their respective sensitivities.

2,594 citationstop 1%

multiple speciesprotein structure

𝕏 PostBluesky