Author

Cecilia N. Amadi

University of ManchesterORCID 0000-0002-2724-4262Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Alexander Fanourakis· 1 shared Andrew W. MunroiD· 1 shared Anthony G. CoyneiD· 1 shared Chris AbelliD· 1 shared Colin LevyiD· 1 shared David LeysiD· 1 shared Fátima Ortega· 1 shared Helena I. BoshoffiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Alexander Fanourakis

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1 paper

Recent·Most cited

Fragment-based development of small molecule inhibitors targeting Mycobacterium tuberculosis cholesterol metabolism

Madeline E. Kavanagh, Kirsty J. McLean, Sophie H. Gilbert, Cecilia N. Amadi, M. Snee, Richard B. Tunnicliffe, Kriti Arora, Helena I. Boshoff, Alexander Fanourakis, María José Rebollo-López, Fátima Ortega, Colin Levy, Andrew W. Munro, David Leys, Chris Abell, Anthony G. Coyne

This paper develops small molecule inhibitors targeting Mtb cholesterol oxidases CYP125 and CYP142, showing potent antimicrobial activity against drug-susceptible and MDR-TB strains.

Journal of Medicinal Chemistry · Jul 14, 2025Peer-reviewedPharmacology & Toxicology