Author

M. Snee

Manchester Academic Health Science CentreORCID 0000-0003-3138-4994Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

M. Snee1 paper

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Colin LevyiD· 2 shared Abigail R. E. RobertsiD· 1 shared Alberto MantovaniiD· 1 shared Alexander Fanourakis· 1 shared Andrew W. MunroiD· 1 shared Anokhi ShahiD· 1 shared Anthony G. CoyneiD· 1 shared Anthony J. DayiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPharmacology & Toxicology

Colin LevyORCID

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2 papers

Recent·Most cited

Pharmacology & ToxicologyJournal of Medicinal ChemistryPeer-reviewedJul 14, 2025

Fragment-based development of small molecule inhibitors targeting Mycobacterium tuberculosis cholesterol metabolism

Madeline E. Kavanagh, Kirsty J. McLean, Sophie H. Gilbert…·Anthony G. Coyne

This paper develops small molecule inhibitors targeting Mtb cholesterol oxidases CYP125 and CYP142, showing potent antimicrobial activity against drug-susceptible and MDR-TB strains.

4 citations

experimental assaydrug response / drug discovery

𝕏 PostBluesky

BiochemistryMatrix BiologyPeer-reviewedJan 13, 2025

The structural organisation of pentraxin-3 and its interactions with heavy chains of inter-alpha-inhibitor regulate crosslinking of the hyaluronan matrix

Anokhi Shah, Xiaoli Zhang, M. Snee…·Anthony J. Day

This paper investigates how PTX3's quaternary structure enables HA crosslinking via interactions with HC1, revealing pH-dependent binding and structural flexibility.

13 citations

humanstructural biology

𝕏 PostBluesky