Ana M.M. Oliveira

This study identifies hippocampal DNA methylation as a mechanism that converts short-lasting into long-lasting memories by promoting systems consolidation and cortical engram stabilization.

This study shows that Dnmt3a1, but not Dnmt3a2, is required for hippocampus-dependent memory through its regulation of Nrp1.

This study shows that biphasic Npas4 expression suppresses fear memory consolidation and promotes behavioral flexibility in mice by facilitating fear extinction.

This study shows that engram reactivation during memory retrieval predicts long-term memory performance in aged mice, with impaired reactivation linked to cognitive decline.

This study identifies MeCP2's role in regulating alternative splicing in the mouse hippocampus during spatial learning and shows its impact on memory consolidation and Rett syndrome pathophysiology.

This study shows that increased Gadd45γ expression in the hippocampus of aged humans and young adult mice impairs spatial memory and disrupts CREB signaling and activity-regulated genes.