Double-strand breaks induce inverted duplication chromosome rearrangements by a DNA polymerase delta and Rad51-dependent mechanism
Amr Al-Zain, Mattie R. Nester, Iffat Ahmed, Lorraine S. Symington
The paper shows that DNA double-strand breaks near inverted repeats drive inverted duplications in Sae2 and Mre11-deficient cells through a mechanism involving DNA polymerase delta and Rad51.
Nature Communications · Nov 2, 2023Peer-reviewedGenetics