Author

Mattie R. Nester

Columbia University Irving Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:yeast· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Lorraine S. SymingtoniD· 2 shared Amr Al-ZainiD· 1 shared Iffat AhmediD· 1 shared Matthew J. JohnsoniD· 1 shared Michael T. KimbleiD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

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2 shared papersGenetics

Lorraine S. SymingtonORCID

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2 papers

Recent·Most cited

GeneticsNature CommunicationsPeer-reviewedNov 2, 2023

Double-strand breaks induce inverted duplication chromosome rearrangements by a DNA polymerase delta and Rad51-dependent mechanism

Amr Al-Zain, Mattie R. Nester, Iffat Ahmed, Lorraine S. Symington

The paper shows that DNA double-strand breaks near inverted repeats drive inverted duplications in Sae2 and Mre11-deficient cells through a mechanism involving DNA polymerase delta and Rad51.

15 citations

yeastexperimental assay

𝕏 PostBluesky

GeneticseLifePeer-reviewedJun 30, 2023

Long-range DNA end resection supports homologous recombination by checkpoint activation rather than extensive homology generation

Michael T. Kimble, Matthew J. Johnson, Mattie R. Nester, Lorraine S. Symington

This study shows that long-range DNA end resection by Exo1 and Sgs1-Dna2 supports homologous recombination through checkpoint activation, not by generating extensive homology.

14 citations

yeastDNA methylation

𝕏 PostBluesky