Author

Sari Pennings

University of EdinburghORCID 0000-0002-2744-1055Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:flow cytometry· 1 Assay:imaging· 1

Frequent Co-Authors

Richard R. MeehaniD· 2 shared Silviya DimovaiD· 2 shared Abdulaziz AlhussiniiD· 1 shared Ailsa Laird· 1 shared Alistair P. D. ElfickiD· 1 shared Andrea CaporaliiD· 1 shared Beatrice VillaniiD· 1 shared C. Roland WolfiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCell Biology

Richard R. MeehanORCID

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2 papers

Recent·Most cited

Development and characterisation of an optimised in vitro differentiation protocol for deriving hepatocyte-like cells from mouse embryonic stem cells

Beatrice Villani, Silviya Dimova, Abdulaziz Alhussini, Andrea Caporali, Congyue Chen, Ailsa Laird, C. Roland Wolf, Alistair P. D. Elfick, Richard R. Meehan, Sari Pennings

This study develops and evaluates two cytokine-based protocols to generate functional hepatocyte-like cells from mouse embryonic stem cells, with the advanced cocktail producing more mature cells.

bioRxiv · May 15, 2026 · PreprintCell Biology

Polycomb Repressive Complexes 1 and 2 are recruited independently to pericentromeric heterochromatin in response to hypomethylation in mouse embryonic stem cells

Silviya Dimova, Olga Stepanova, David Hay, Katherine E. Pickup, Philippe Emmanuel Gautier, Laura C. Murphy, Yatendra Kumar, Ian R. Adams, Sari Pennings, Richard R. Meehan

The paper shows that PRC1 and PRC2 are independently recruited to hypomethylated pericentromeric heterochromatin in mESCs without requiring specific mediators.

bioRxiv · Nov 14, 2025 · PreprintMolecular Biology