Yatendra Kumar

The paper shows that transcription terminators facilitate RNA polymerase III recycling, enhancing chromatin transcription and linking transcriptional activation with chromatin remodeling in vivo.

The paper identifies H3K115ac enrichment at fragile nucleosomes in promoters and enhancers, suggesting its role in nucleosome destabilization and regulatory element identification.

The paper shows that PRC1 and PRC2 are independently recruited to hypomethylated pericentromeric heterochromatin in mESCs without requiring specific mediators.

This study shows intermittent fasting changes chromatin accessibility and gene expression in brain and muscle tissues of mice, affecting metabolic and functional pathways.

The paper shows TPR is required for early NF-κB activation during oncogene-induced senescence, leading to cytoplasmic chromatin fragment formation and SASP activation.

The paper shows that cell proliferation in human embryonic stem cell-derived endodermal progenitors primes enhancer landscapes for organ-specific differentiation by modulating chromatin accessibility and enhancer decommissioning.

The paper identifies mutational biases at germline regulatory sites, showing increased structural variants and insertions at transcription factor binding sites, with implications for evolution and disease.

This study shows cohesin, but not CTCF, is required for activation of genes by distant enhancers, while close enhancers can function without cohesin.