PhysiologyArteriosclerosis Thrombosis and Vascular BiologyPeer-reviewed
Extracellular vesicles from preeclampsia disrupt the blood-brain barrier via reduced claudin-5: potential role of vascular endothelial growth factor
Hermes Sandoval, Belén Ibáñez, Moisés Contreras…·Carlos Escudero
This study shows that extracellular vesicles from preeclampsia and hypoxic placentae reduce claudin-5 in the blood-brain barrier, potentially via VEGF, leading to BBB disruption and neurological deficits.