Carlos Escudero

This paper shows boldine prevents diabetes-induced skeletal muscle dysfunction by inhibiting large-pore channels and reducing inflammation and lipid accumulation.

This study shows that TSP-1 from preeclampsia affects brain endothelial function by reducing angiogenesis and altering signaling pathways.

This study identifies differentially expressed placental exomiRs in preeclampsia and links them to maternal brain dysregulation through bioinformatic analysis and proteomic integration.

This study examines sex-specific neurovascular and cognitive deficits in offspring of preeclampsia using a murine model, finding impaired vascular function and cognition, more severe in males and females respectively.

This study shows that plasma, not extracellular vesicles, disrupts the blood-brain barrier in eclampsia, and magnesium sulfate reduces this effect by decreasing vesicle uptake and altering their protein content.

This study shows that extracellular vesicles from preeclampsia and hypoxic placentae reduce claudin-5 in the blood-brain barrier, potentially via VEGF, leading to BBB disruption and neurological deficits.

This study shows hsa-miR-9-5p from preeclampsia placental EVs reduces brain endothelial cell proliferation and migration while modulating angiogenic factors.