Francisco Nualart

This study examines sex-specific neurovascular and cognitive deficits in offspring of preeclampsia using a murine model, finding impaired vascular function and cognition, more severe in males and females respectively.

This study shows that extracellular vesicles from preeclampsia and hypoxic placentae reduce claudin-5 in the blood-brain barrier, potentially via VEGF, leading to BBB disruption and neurological deficits.