Rasika M. Harshey

Mu-seq reveals previously undetected long-range contact patterns in the Escherichia coli nucleoid

Mu-seq maps long-range DNA-DNA contacts in E. coli without crosslinking, revealing new interaction patterns not detectable by Hi-C.

Aer is a bidirectional redox sensor mediating negative chemotaxis to antibiotic-induced ROS in E. coli

This study shows that Aer in E. coli functions as a bidirectional redox sensor mediating negative chemotaxis to antibiotic-induced ROS and enables bacterial movement away from ROS-generating antibiotics.

Texas 2-Step: A new Model for YcgR::c-di-GMP Action at the Flagellar Motor

The paper proposes the Texas 2-Step model to explain how YcgR modulates flagellar motor rotation in E. coli by interacting with MotA and FliG through conformational changes.

Membrane-associated σ factors disrupt rRNA operon clustering in E. coli

The paper shows that membrane-associated σ factors disrupt rRNA operon clustering in E. coli by interacting with core-RNAP and competing with σD.

c-di-GMP is required for swarming motility in E. coli: a role for DgcO and colanic acid

This study shows that c-di-GMP is required for swarming motility in E. coli, with DgcO promoting colanic acid production, which has surfactant properties aiding surface navigation.

Phage Mu Utilizes the Sliding Clamp for Late Gene Transcription

This study shows that MuC, a phage Mu protein, interacts with the beta sliding clamp to facilitate late gene transcription in E. coli.

Flagellar Motility is Mutagenic

This study shows that flagellar motility in E. coli increases mutation rates, suggesting it influences bacterial evolution rates.