Author

Ashot Papikian

California Institute of TechnologyORCID 0000-0002-2801-6341Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:gene regulatory network inference· 2 Approach:genetic perturbation / CRISPR· 2 Assay:CRISPR screen· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Jake HarrisiD· 1 shared Esther LeemiD· 1 shared Gözde S. DemireriD· 1 shared Hannah FryeriD· 1 shared Ian R. HendersoniD· 1 shared Jenia BinenbaumiD· 1 shared Kimberley T MuchenjeiD· 1 shared Linhao XuiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPlant Biology

C. Jake HarrisORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

CRISPR-Associated Transposases Enable Programmable DNA Integration in Plants

Yunqing Wang, Kimberley T Muchenje, Ashot Papikian, Mark G. Legendre, Esther Leem, Gözde S. Demirer

This study demonstrates the use of CRISPR-associated transposases for programmable DNA integration in plants, achieving efficient chromosomal and episomal integration in Arabidopsis and Nicotiana benthamiana.

bioRxiv · Jul 16, 2026 · PreprintBioengineering

CRISPR targeting of H3K4me3 activates gene expression and unlocks centromere-proximal crossover recombination in Arabidopsis

Jenia Binenbaum, Vanda Gabriela Adamkova, Hannah Fryer, Linhao Xu, Nicola Gorringe, Piotr Włodzimierz, Robin Burns, Ashot Papikian, Steven E. Jacobsen, Ian R. Henderson, C. Jake Harris

This study uses CRISPR to target H3K4me3 methyltransferases in Arabidopsis, showing activation of gene expression and increased meiotic crossover recombination near centromeres.

Nature Communications · Oct 31, 2025Peer-reviewedPlant Biology