Author

Nicola Gorringe

University of CambridgeORCID 0000-0003-1389-7630Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Genomics· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 3 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Ian R. HendersoniD· 4 shared Robin BurnsiD· 4 shared Piotr WłodzimierziD· 3 shared Katharine M. JenikeiD· 2 shared Matthew NaishiD· 2 shared Stephanie D. ToppiD· 2 shared Alexandros BousiosiD· 1 shared André MarquesiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersGenetics

Ian R. HendersonORCID

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4 papers

Recent·Most cited

GenomicsbioRxivPreprintSep 23, 2026

✦ In-depth digest

An atlas of eukaryotic centromere architecture reveals recurrent evolutionary dynamics

Piotr Włodzimierz, Estela Pérez-Román, Jacob Gonzalez Isa…·Ian R. Henderson

Across 325 Darwin Tree of Life genomes, satellite-array and transposon-cluster centromeres are phylogenetically scattered, fitting a model of repeated interconversion; satellites share higher-order repeat structure but not sequence.

1 citation

multiple speciesplant (other)

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GeneticsbioRxivPreprintJul 24, 2026

CRISPR-mediated centromere fission generates neo-chromosomes with distorted meiotic inheritance in Arabidopsis

Robin Burns, Terezie M. Mandáková, Chris Morgan…·Ian R. Henderson

This study uses CRISPR to reposition centromeres in Arabidopsis, showing how neo-chromosomes with altered centromere positions lead to meiotic segregation distortion and aneuploidy.

DOI 10.64898/2026.07.24.740321

Arabidopsisexperimental assay

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GeneticsGeneticsPeer-reviewedDec 8, 2025

Natural variation modifies centromere proximal meiotic crossover frequency and segregation distortion in Arabidopsis thaliana

Nicola Gorringe, Stephanie D. Topp, Robin Burns…·Ian R. Henderson

The paper investigates how natural genetic variation in Arabidopsis thaliana affects centromere-proximal crossover frequency and segregation distortion during meiosis.

3 citations

ArabidopsisDNA methylation

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Plant BiologyNature CommunicationsPeer-reviewedOct 31, 2025

CRISPR targeting of H3K4me3 activates gene expression and unlocks centromere-proximal crossover recombination in Arabidopsis

Jenia Binenbaum, Vanda Gabriela Adamkova, Hannah Fryer…·C. Jake Harris

This study uses CRISPR to target H3K4me3 methyltransferases in Arabidopsis, showing activation of gene expression and increased meiotic crossover recombination near centromeres.

15 citationstop 4%

Arabidopsisproteomics

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