Author

Tarsisius T. Tiyani

The Graduate Center, CUNYORCID 0000-0002-2806-4079Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

Eta A. IsiorhoiD· 1 shared Jason S. NagatiiD· 1 shared Joseph A. GarciaiD· 1 shared Joseph D. ClossoniD· 1 shared Kevin H. GardneriD· 1 shared Leandro Pimentel MarcelinoiD· 1 shared Meiling ZhangiD· 1 shared Xingjian XuiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Eta A. IsiorhoORCID

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1 paper

Recent·Most cited

Context-Dependent Variability Of HIF Heterodimers Influences Interactions With Macromolecular And Small Molecule Partners

Joseph D. Closson, Xingjian Xu, Meiling Zhang, Tarsisius T. Tiyani, Leandro Pimentel Marcelino, Eta A. Isiorho, Jason S. Nagati, Joseph A. Garcia, Kevin H. Gardner

This study investigates how context-dependent variability in HIF heterodimers affects their interactions with DNA, small molecules, and coactivators, revealing a novel 'dimer-of-heterodimers' structure.

Proceedings of the National Academy of Sciences · Apr 28, 2026Peer-reviewedBiochemistry