Author

Jason S. Nagati

Columbia University Irving Medical CenterORCID 0000-0002-4507-6581Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

Eta A. IsiorhoiD· 1 shared Joseph A. GarciaiD· 1 shared Joseph D. ClossoniD· 1 shared Kevin H. GardneriD· 1 shared Leandro Pimentel MarcelinoiD· 1 shared Meiling ZhangiD· 1 shared Tarsisius T. TiyaniiD· 1 shared Xingjian XuiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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8 top collaborators · 28 mutual co-author links

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1 shared paperBiochemistry

Eta A. IsiorhoORCID

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1 paper

Recent·Most cited

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedApr 28, 2026

Context-Dependent Variability Of HIF Heterodimers Influences Interactions With Macromolecular And Small Molecule Partners

Joseph D. Closson, Xingjian Xu, Meiling Zhang…·Kevin H. Gardner

This study investigates how context-dependent variability in HIF heterodimers affects their interactions with DNA, small molecules, and coactivators, revealing a novel 'dimer-of-heterodimers' structure.

DOI 10.1073/pnas.2514042123

humanstructural biology

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