High-accuracy mapping of human and viral direct physical protein-protein interactions using the novel computational system AlphaFold-pairs
Christian Poitras, Felix Lamontagne, Nathalie Grandvaux, Hao Song, Maxime Pinard, Benoit Coulombe
The paper introduces AlphaFold-pairs, a computational method to predict protein-protein interactions, validated on human and viral systems, revealing new interactions in SARS-CoV-2 and Influenza A virus.
bioRxiv · Aug 29, 2023 · PreprintBioinformatics