A funnel approach to enable analyses of epitope-specific human CD4 T cells specific for influenza and SARS-CoV-2.
Katherine A. Richards, Robert C. Mettelman, Kiley Trombley…·Andrea J. Sant
The paper introduces a funnel approach to identify epitope-specific CD4 T cells for influenza and SARS-CoV-2 by narrowing down potential epitopes using HLA-DR transgenic mice and ELISpot assays.