Andrea J. Sant

The paper introduces a funnel approach to identify epitope-specific CD4 T cells for influenza and SARS-CoV-2 by narrowing down potential epitopes using HLA-DR transgenic mice and ELISpot assays.

This study examines how prior influenza infection memory affects CD4 T cell responses to a recombinant influenza vaccine in a mouse model, revealing shifts in T cell fate and function.