Filio Billia

This study shows that LTBP2 promotes fibrosis in remote myocardium after MI by sequestering latent TGF-β, and its deletion reduces fibrosis and improves cardiac function.

This study identifies miR-9-5p as a regulator of cardiomyocyte hypertrophy and contractility in HCM using iPSC models and miRNA profiling.

This study identifies DNA methylation instability in blood cells linked to aging and disease, showing age-related instability and associations with cardiovascular disease and cancer.

This paper demonstrates that lipid nanoparticle-delivered miR-187 reduces inflammation and improves cardiac function in sepsis models.

This study shows that a myosin ATPase inhibitor reverses HCM phenotypes in pediatric iPSC-cardiomyocytes, with effects dependent on the underlying genetic variant.