Dona Flor and her two husbands: Discovery of novel HDAC6/AKT2 inhibitors for myeloid cancer treatment
Karoline B. Waitman, Holli‐Joi Martin, Jorge Antonio Elias Godoy Carlos, Rodolpho C. Braga, Vinícius A.M. Souza, Cleber Camilo Melo-Filho, Sebastian Hilscher, Mônica F. Z. J. Toledo, Maurício T. Tavares, Letícia Veras Costa-Lotufo, João Agostinho Machado‐Neto, Mike Schutkowski, Wolfgang Sippl, Thales Kronenberger, Vinícius M. Alves, , Eugene N. Muratov
The paper uses machine learning to identify novel HDAC6/AKT2 inhibitors for myeloid cancer treatment, finding compounds with potent anticancer activity.
Computers in Biology and Medicine · Dec 5, 2024Peer-reviewedCancer Biology