Structural Basis for the Activation of Proteinase-Activated Receptors (PARs) by Endogenous Ligands
Zongyang Lyu, Xiaoxuan Lyu, Andrey G. Malyutin…·Yanyong Kang
This study presents structural insights into PAR1 and PAR2 activation by endogenous ligands, revealing a novel mechanism and potential targets for therapeutic development.