Author

Erin S. Reynolds

SUNY Upstate Medical UniversityORCID 0000-0002-2847-0982Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Hongpeng JiaiD· 2 shared Ikechukwu B. Jacob· 2 shared Saravanan ThangamaniiD· 2 shared Akinkunmi O. LawaliD· 1 shared Amanda GemmitiiD· 1 shared Brian D. NicholasiD· 1 shared Emerson M. Kopsack· 1 shared Guirong WangiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Hongpeng JiaORCID

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2 papers

Recent·Most cited

ImmunologyFrontiers in ImmunologyPeer-reviewedApr 2, 2025

Differential Immunoregulation by Human Surfactant Protein A Variants Determines Severity of SARS-CoV-2-induced Lung Disease

Ikechukwu B. Jacob, Akinkunmi O. Lawal, Salma S. Mahmoud…·Guirong Wang

This study shows that different human SP-A variants affect SARS-CoV-2-induced lung disease severity by altering viral infectivity and immune gene expression.

4 citations

mousebulk RNA-seq

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Molecular BiologybioRxivPreprintApr 3, 2023

Human Surfactant Protein A Alleviates SARS-CoV-2 Infectivity in Human Lung Epithelial Cells

Ikechukwu B. Jacob, Amanda Gemmiti, Weichuan Xiong…·Guirong Wang

This study shows human SP-A binds SARS-CoV-2 S protein and hACE2, inhibiting viral infectivity and reducing viral load in lung cells, and suggests SP-A levels in saliva correlate with COVID-19 severity.

4 citations

humanstatistical model

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