This study shows that different human SP-A variants affect SARS-CoV-2-induced lung disease severity by altering viral infectivity and immune gene expression.

Frontiers in Immunology · Apr 2, 2025Peer-reviewedImmunology

Insulin/IGF signaling and TOR promote vitellogenesis via inducing juvenile hormone biosynthesis

Shiming Zhu, Fangfang Liu, Huanchao Zeng, Na Li, Chonghua Ren, Yun‐Lin Su, Shutang Zhou, Guirong Wang, Subba Reddy Palli, Jian Wang, Yiru Qin, Sheng Li

This study shows that JH signaling induces vitellogenesis, while IIS and TOR promote it indirectly by enhancing JH biosynthesis in American cockroaches.

Development · Oct 15, 2020Peer-reviewedDevelopmental Biology

Regulation of olfactory-based sex behaviors in the silkworm by genes in the sex-determination cascade

Jun Qiang Xu, Wei Liu, Dehong Yang, Shuqing Chen, Kai Chen, Zulian Liu, Yang Xu, Jing Meng, Guan‐Heng Zhu, Shuanglin Dong, Yong Zhang, Shuai Zhan, Guirong Wang, Yongping Huang

The paper identifies two genetic pathways in silkworms that regulate olfactory-based sexual behaviors through specific pheromone perception genes.

PLoS Genetics · Jun 10, 2020Peer-reviewedGenetics

High-depth resequencing reveals hybrid population and insecticide resistance characteristics of fall armyworm (Spodoptera frugiperda) invading China

Lei Zhang, Bo Liu, Weigang Zheng, Conghui Liu, Dandan Zhang, Shengyuan Zhao, Pengjun Xu, Kenneth L. Wilson, Amy J. Withers, Christopher M. Jones, Judith A. Smith, Gilson Chipabika, Donald L. Kachigamba, Kiwoong Nam, Emmanuelle d’Alençon, , Yutao Xiao

This study uses high-depth resequencing to analyze genetic diversity and insecticide resistance in fall armyworm populations invading China, revealing hybrid origins and resistance patterns.

bioRxiv · Nov 29, 2019 · PreprintGenomics