Michelle A. Tran

The role of Fragile X in the control of vertebrate spinal cord networks

This study investigates the role of Fmr1 in spinal cord circuits and finds that motor impairments in FXS may arise from supraspinal dysfunction rather than intrinsic spinal defects.

Restoration of locomotor function following stimulation of the A13 region in Parkinson's mouse models

This study shows that stimulating the A13 region in Parkinson's mouse models improves locomotor function and reduces bradykinesia by restoring motor function through neural remodeling.

Episodic rhythmicity is generated by a distributed neural network in the developing mammalian spinal cord

This study shows that episodic rhythmicity in the developing mammalian spinal cord arises from a distributed network of interneurons, with afferent control and VLF projections playing key roles.

Substantia nigra degradation results in widespread changes in medial zona incerta afferent and efferent connectomics

The paper investigates changes in the connectome of the A13 nucleus in Parkinson's disease models, finding widespread reconfiguration of afferent and efferent projections following nigrostriatal degeneration.

A point mutation in Ttc26 causes lumbar spinal cord fusion and synchronous hind-limb locomotion in hop mice