Patrick J. Whelan

This study investigates the role of Fmr1 in spinal cord circuits and finds that motor impairments in FXS may arise from supraspinal dysfunction rather than intrinsic spinal defects.

This study shows that stimulating the A13 region in Parkinson's mouse models improves locomotor function and reduces bradykinesia by restoring motor function through neural remodeling.

This study shows that episodic rhythmicity in the developing mammalian spinal cord arises from a distributed network of interneurons, with afferent control and VLF projections playing key roles.

The paper investigates how h- and Na+/K+ pump currents contribute to episodic and continuous rhythmic activities in spinal motor networks using computational models and experimental validation.

The paper investigates changes in the connectome of the A13 nucleus in Parkinson's disease models, finding widespread reconfiguration of afferent and efferent projections following nigrostriatal degeneration.

This study investigates how dopamine receptors regulate spinal network output in neonatal mice, revealing concentration-dependent excitatory and inhibitory effects mediated by D1 and D2 receptors during low excitability states.