ImmunologyImmunotherapy AdvancesPeer-reviewed
Interaction with tumor cell spheroids induces suppression in primary human cytotoxic T cells
Amal Alsubaiti, Hanin Alamir, Lan Huynh…·Christoph Wülfing
The paper generates and characterizes primary human cytotoxic T cells with suppressed function in vitro, showing their resemblance to exhausted tumor-infiltrating CTL and identifying factors affecting their effector function.
DOI 10.1093/immadv/ltaf023