Richard F. Campbell

Laboratory evolution from social to solitary behavior in the N2 reference strain is unnecessary for its fitness advantages

This study shows that fitness advantages in the N2 C. elegans strain arise from genetic changes in npr-1 and glb-5, which affect O2 sensing and pheromone circuits, not directly from solitary feeding behavior.

Modeling of a negative feedback mechanism explains age-dependent genetic architecture in reproduction in domesticated C. elegans strains

The paper models a negative feedback mechanism in C. elegans to explain age-dependent genetic architecture in reproduction, identifying how epistasis and sperm use influence egg-laying rates.