Lijiang Long

A secreted endoribonuclease ENDU-2 from the soma protects germline immortality in C. elegans

This study identifies ENDU-2, a secreted RNase in C. elegans, that maintains germline immortality by regulating mRNA abundance and preventing soma-specific gene misexpression in the germline.

Quantitative benzimidazole resistance and fitness effects of parasitic nematode beta-tubulin alleles

This study demonstrates that five beta-tubulin alleles confer benzimidazole resistance in parasitic nematodes and shows that E198V reduces fitness in the absence of the drug.

Laboratory evolution from social to solitary behavior in the N2 reference strain is unnecessary for its fitness advantages

This study shows that fitness advantages in the N2 C. elegans strain arise from genetic changes in npr-1 and glb-5, which affect O2 sensing and pheromone circuits, not directly from solitary feeding behavior.