Author

Manohar Ratnam

Wayne State UniversityORCID 0000-0002-2866-7136Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Charles E. DuckeriD· 1 shared Claire L. SoaveiD· 1 shared Jing LiiD· 1 shared Lisa PoliniD· 1 shared Luke PardyiD· 1 shared Peter E. ShawiD· 1 shared Rahul S. KhupseiD· 1 shared Seongho KimiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Charles E. DuckerORCID

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1 paper

Recent·Most cited

A Novel Drug Candidate that Selectively Targets the Critical Androgen Receptor-ELK1 Growth Axis in Advanced and Drug-Resistant Prostate Cancer

Claire L. Soave, Lisa Polin, Charles E. Ducker, Vy Ong, Seongho Kim, Luke Pardy, Jing Li, Xun Bao, Yanfang Huang, Peter E. Shaw, Rahul S. Khupse, Manohar Ratnam

This paper develops a new compound KCI838 that selectively inhibits the AR-ELK1 axis in prostate cancer, showing potent anti-tumor activity in resistant models.

bioRxiv · May 29, 2026 · PreprintCancer Biology