Predicting Individual Cell Division Events from Single-Cell ERK and Akt Dynamics
Alan D. Stern, Gregory R. Smith, LETÍCIA VITÓRIA DA SILVA SANTOS…·Marc R. Birtwistle
The paper uses single-cell imaging and machine learning to predict cell division from ERK and Akt activity dynamics in MCF10A cells, finding ERK alone predicts division with AUC=0.74.