Jerry E. Chipuk

The paper identifies CDL36, a compound that inhibits cell death by preventing mitochondrial outer membrane permeabilization, with potent cytoprotection against doxorubicin-induced toxicity.

This study surveys LGBTQ+ biologists to assess workplace climate and belonging, finding lower morale and exclusionary experiences among transgender and gender non-conforming scientists.

This paper develops a human recombinant antibody (3G11) specific for DRP1-S616 phosphorylation, demonstrating its utility in detecting mitochondrial division in cancer, particularly in BRAFV600E-associated diseases.

The paper identifies a hydrophobic funnel in BAX that binds 2t-hexadecenal, enhancing BAX activation with BIM, and shows proline 168 regulates this interaction.

This study shows that the developmental stage of hematopoietic stem cells influences leukemic transformation, lineage hierarchy, and therapy response in pediatric leukemia.

This study investigates how RvD1 reduces inflammation, cell death, and fibrosis in MASH by targeting Stat1, ER stress, and MMP pathways.

This study shows that leukemia cells rely on increased mitochondrial respiration for survival when glucose uptake is acutely inhibited by KL-11743.

The paper shows that variable mitochondria abundance affects cell survival and fractional cell death response to TRAIL through Bax effective concentration variation.