IROP: Ionic Regulation of Permeation for High-Yield AAV Purification
Deepraj Sarmah, Scott M. Husson
The paper introduces IROP, a new purification method for AAV that uses ionic strength modulation to achieve high yield and impurity removal.
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Clemson UniversityORCID 0000-0003-0212-7120Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
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Deepraj Sarmah, Scott M. Husson
The paper introduces IROP, a new purification method for AAV that uses ionic strength modulation to achieve high yield and impurity removal.
Marc R. Birtwistle, Jonah R. Huggins, Cameron O. Zadeh…·Delphine Dean
This paper introduces a 96-sample western blot format that improves efficiency and capacity while maintaining compatibility with standard protocols.
Deepraj Sarmah, Wesley O. Meredith, Ian K. Weber…·Marc R. Birtwistle
The paper predicts cancer cell responses to drug combinations using a temporal cell state network model based on single drug dose responses and cell cycle transitions.
Deepraj Sarmah, Gregory R. Smith, Mehdi Bouhaddou…·Marc R. Birtwistle
This paper introduces DL-MRA, a method to infer network structures from perturbation time course data, showing it can robustly identify small networks but has limitations for signaling networks.
Alan D. Stern, Gregory R. Smith, LETÍCIA VITÓRIA DA SILVA SANTOS…·Marc R. Birtwistle
The paper uses single-cell imaging and machine learning to predict cell division from ERK and Akt activity dynamics in MCF10A cells, finding ERK alone predicts division with AUC=0.74.