Comprehensive comparison between azacytidine and decitabine treatment in an acute myeloid leukemia cell line
Tina Aumer, Constanze B. Gremmelmaier, Leander Simon Runtsch, Johannes C. Pforr, G. Nur Yeşiltaç, Stefanie Kaiser, Franziska R. Traube
This study compares the effects of azacytidine and decitabine on an acute myeloid leukemia cell line, finding that decitabine induces apoptosis while azacytidine does not, linked to differences in hydroxy-methyl-dC levels.
Clinical Epigenetics · Sep 11, 2022Peer-reviewedMolecular Biology