Author

Sara J. Clasen

Max Planck Institute for BiologyORCID 0000-0002-2888-7040Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

Ruth E. LeyiD· 2 shared Andrea QuagliarielloiD· 1 shared Antton AlberdiiD· 1 shared Chiara FaveroiD· 1 shared Chinmay Kumar DwibediiD· 1 shared Felipe MerinoiD· 1 shared Fredrik BäckhediD· 1 shared Gaohua Yang· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

Ruth E. LeyORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintFeb 28, 2025

Characterization and description of Clostridium filamentum ETTB, a novel gut bacterium with TLR5 modulating properties

Kassem Makki, Maria Elena Martino, Antton Alberdi…·Fredrik Bäckhed

This study isolates and characterizes a novel Clostridium species, C. filamentum ETTB, which modulates the TLR5 pathway in host cells and has distinct genomic features compared to related species.

DOI 10.1101/2025.02.28.640726

humanmetagenomics

BiochemistrybioRxivPreprintDec 9, 2024

Kinetic and structure-based comparisons of silent and stimulatory flagellin interactions with TLR5

Michael E. W. Bell, Miriam Haag, Sara J. Clasen…·Ruth E. Ley

The paper compares the binding kinetics and structural features of silent and stimulatory flagellin variants with TLR5, identifying structural differences that explain their distinct immune responses.

2 citations

experimental assayhost-pathogen & immune response