BiochemistrySciencePeer-reviewed
Mining the CRBN Target Space Redefines Rules for Molecular Glue-induced Neosubstrate Recognition
Georg Petzold, Pablo Gaínza, Stefano Annunziato…·Sharon A. Townson
The paper predicts over 1,400 CRBN-compatible β-hairpin G-loop proteins and validates 22 neosubstrates, redefining rules for molecular glue-induced degradation.
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