Author

Balthasar A. Heesters

Utrecht UniversityORCID 0000-0002-2909-8481Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Rogier W. SandersiD· 2 shared Tom G. CanielsiD· 2 shared Anne L. M. KimpeliD· 1 shared Arash GrakouiiD· 1 shared Arpan PradhaniD· 1 shared Christoph MattiiD· 1 shared Enrico C. J. M. VerpaleniD· 1 shared Geert‐Jan BoonsiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Rogier W. SandersORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Fusion of Complement Fragment C3d Enhances Germinal Center Responses to HIV-1 Envelope Glycoproteins

Marlon de Gast, Sara Hernández‐Pérez, Arpan Pradhan, Sabine Kruijer, Wouter Olijhoek, Isabel J. L. Baken, Christoph Matti, Martijn Breeuwsma, Zhang Sung Tean, Willemijn J. C. van Keizerswaard, Samantha Zoomer, Judith A. Burger, Tom G. Caniels, Kwinten Sliepen, Ronald Derking, , Marit J. van Gils

This study shows that fusing C3d to HIV-1 Env immunogens enhances germinal center responses and improves vaccine immunogenicity.

bioRxiv · Jun 28, 2025 · PreprintImmunology

The SARS-CoV-2 spike N-terminal domain engages 9-O-acetylated α2-8-linked sialic acids

Ilhan Tomris, Luca Unione, Linh Nguyen, Pouya Zaree, Kim M. Bouwman, Lin Liu, Zeshi Li, Jelle A. Fok, María Ríos Carrasco, Roosmarijn van der Woude, Anne L. M. Kimpel, Mirte W. Linthorst, Sinan E. Kilavuzoglu, Enrico C. J. M. Verpalen, Tom G. Caniels, , Robert P. de Vries

This paper identifies 9-O-acetylated sialic acids as a ligand for the SARS-CoV-2 NTD, revealing a dual-receptor functionality in the S1 domain that was rapidly selected against.

ACS Chemical Biology · Apr 27, 2023Peer-reviewedMolecular Biology