The HCoV-HKU1 N-terminal domain binds a wide range of 9-O-acetylated sialic acids presented on different glycan cores
Ilhan Tomris, Anne L. M. Kimpel, Ruonan Liang…·Robert P. de Vries
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Utrecht UniversityORCID 0000-0003-2151-5604Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
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Ilhan Tomris, Anne L. M. Kimpel, Ruonan Liang…·Robert P. de Vries
Ilhan Tomris, Roosmarijn van der Woude, Rebeca de Paiva Fróes Rocha…·Robert P. de Vries
The paper develops fluorescent protein fusions to study receptor binding of viral envelope proteins in cells.
Ilhan Tomris, Luca Unione, Linh Nguyen…·Robert P. de Vries
This paper identifies 9-O-acetylated sialic acids as a ligand for the SARS-CoV-2 NTD, revealing a dual-receptor functionality in the S1 domain that was rapidly selected against.
Cindy M. Spruit, Xueyong Zhu, Ilhan Tomris…·Robert P. de Vries
The paper investigates how avian H7 influenza A viruses can bind NeuGc through specific mutations, revealing insights into viral adaptation to NeuGc receptors.
Kim M. Bouwman, Ilhan Tomris, Hannah L. Turner…·Robert P. de Vries
The paper demonstrates that fully glycosylated trimeric RBD proteins of SARS-CoV-2 bind more effectively to ACE2 compared to monomeric or immaturely glycosylated variants.