Author

Richard A. Padgett

Cleveland ClinicORCID 0000-0002-2910-1134Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1 Organism:human· 1 Organism:multiple species· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Anthony J. Wynshaw-BorisiD· 1 shared Courtney E. HershbergeriD· 1 shared Devlin C. MoyeriD· 1 shared Filomena PirozziiD· 1 shared Graham E. LarueiD· 1 shared Jagjit Singh· 1 shared Noah J. DanielsiD· 1 shared Rodrigo Lopez-GonzaleziD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 16 mutual co-author links

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1 shared paperNeuroscience

Anthony J. Wynshaw-BorisORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintDec 29, 2022

MOPD I patient-derived cerebral organoids model microcephaly showing premature neurogenesis due to disrupted mitotic spindle orientation.

Jagjit Singh, Noah J. Daniels, Filomena Pirozzi…·Richard A. Padgett

This study uses patient-derived cerebral organoids to show that MOPD I mutations cause disrupted mitotic spindle orientation, leading to premature neurogenesis and cortical layering defects.

1 citation

humanscRNA-seq

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GenomicsNucleic Acids ResearchPeer-reviewedMay 21, 2020

Updated Database and Evolutionary Dynamics of U12-Type Introns

Devlin C. Moyer, Graham E. Larue, Courtney E. Hershberger…·Richard A. Padgett

The paper updates the Intron Annotation and Orthology Database and supports the class conversion model for U12-type intron evolution.

65 citations

multiple speciesstatistical model

𝕏 PostBluesky