Patterns of extreme outlier RNA expression in population data reveal sporadic over-activation of genes with co-regulated modules in subsets of individuals
Chen Xie, Sven Künzel, Wenyu Zhang, Cassandra A. Hathaway, Shelley S. Tworoger, Diethard Tautz
The paper identifies sporadic over-activation of co-regulated genes with extreme outlier RNA expression in multiple species and tissues, showing these patterns are not inherited but may reflect gene regulatory network dynamics.
bioRxiv · Oct 4, 2024 · PreprintGenomics