Author

Diana C. West-Szymanski

University of ChicagoORCID 0000-0002-2933-1159Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:DNA methylation· 2 Organism:human· 2 Approach:deep learning· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Chuan HeiD· 2 shared Marc BissonnetteiD· 2 shared Urszula DoughertyiD· 2 shared Wei ZhangiD· 2 shared Xiaolong CuiiD· 2 shared Zhou ZhangiD· 2 shared Zifeng DengiD· 2 shared Akushika KwesiiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Chuan HeORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 18, 2025

Discovery of circulating cell-free DNA 5hmC biomarkers for peritoneal metastasis in colorectal and appendiceal cancer

Yuri Malina, Lu Gao, Ankit Dhiman…·Kiran Kalyan Turaga

This study uses 5hmC-Seal technology to detect 5hmC signatures in cfDNA from plasma, identifying peritoneal metastases in CRC and AA with high sensitivity but moderate specificity.

DOI 10.1101/2025.09.18.676945

humanDNA methylation

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GenomicsbioRxivPreprintFeb 25, 2024

Machine learning identifies cell-free DNA 5-hydroxymethylation biomarkers that detect occult colorectal cancer in PLCO Screening Trial subjects

Diana C. West-Szymanski, Zhou Zhang, Xiaolong Cui…·Wei Zhang

This study uses machine learning to identify 5-hydroxymethylation biomarkers in cell-free DNA that can detect occult colorectal cancer up to 36 months before diagnosis.

3 citations

humanDNA methylation

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