Developmental BiologybioRxivPreprint
DNA replication is dispensable for developmental progression, but required for heterochromatin organization at mouse zygotic genome activation
Aurora Arroyo-Jimenez, Alicia Gallego, Antonio Barral…·Marta Portela
This study shows that DNA replication is not required for early mouse embryo development but is necessary for maintaining heterochromatin organization during zygotic genome activation.
DOI 10.64898/2026.09.14.751383