Javier Isoler‐Alcaráz

Slow RNAPII elongation enhances naive-pluripotency rewiring while preserving replication fork speed

The paper shows that slowing RNAPII elongation during cell state transitions enhances naive pluripotency acquisition while maintaining replication fork speed.

EpiFlow: multidimensional single-cell epigenetic profiling by spectral flow cytometry

EpiFlow quantifies 16 epigenetic markers per cell using spectral flow cytometry, showing broad applicability across species and biological processes.

Histone H1 regulates non-coding RNA turnover on chromatin in a m6A-dependent manner

This study shows histone H1 regulates non-coding RNA turnover on chromatin through m6A modification, affecting replication-transcription conflicts.