Author

Lourdes Sriraja

European Bioinformatics InstituteORCID 0000-0002-2940-2068Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Evangelia PetsalakiiD· 2 shared Adriano Velasque WerhliiD· 1 shared Andreas O. Helbig· 1 shared Cunjie ZhangiD· 1 shared Frederick P. RothiD· 1 shared Gerald D. Gish· 1 shared Karen ColwilliD· 1 shared Kristina LorenzeniD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBioinformatics

Evangelia PetsalakiORCID

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2 papers

Recent·Most cited

Phosphoproteomics data-driven signalling network inference: does it work?

Lourdes Sriraja, Adriano Velasque Werhli, Evangelia Petsalaki

This study evaluates six pairwise measures for predicting kinase-substrate and substrate-substrate associations from phosphoproteomics data, finding poor performance but improved results with sequence similarity filtering.

Computational and Structural Biotechnology Journal · Dec 15, 2022Peer-reviewedBioinformatics

Decoding the functional Fes kinase signaling network topology in a lymphocyte model

Andreas O. Helbig, Michael Kofler, Gerald D. Gish, Lourdes Sriraja, Kristina Lorenzen, Monika Tucholska, Cunjie Zhang, Frederick P. Roth, Tony J. Pawson, Karen Colwill, Evangelia Petsalaki

The paper identifies c-Fes kinase substrates and shows how c-Fes and Src signaling balance regulates CD19 levels and influences B-cell receptor signaling.

bioRxiv · Apr 29, 2020 · PreprintSystems Biology