PARylation in Parkinson's disease: a bridge between Lewy body formation and neuronal cell death
Claudia Novello, Federica Giampietro, Alessandra Maria Calogero…·Samanta Mazzetti
This study investigates the role of PARylation in Parkinson's disease by analyzing post-mortem brain samples, finding PAR accumulation precedes α-synuclein aggregation and contributes to Lewy body formation and neuronal cell death.