Hyperactivation of MEK1 in cortical glutamatergic neurons results in projection axon deficits and aberrant motor learning
George R. Bjorklund, Katherina P. Rees, Kavya Balasubramanian…·Jason M. Newbern
This study shows that hyperactivation of MEK1 in cortical glutamatergic neurons leads to axon outgrowth deficits and impaired motor learning, but not locomotor activity.