Sara J. Knowles

This study shows that reducing tau mitigates transcriptomic and behavioral issues in an Alzheimer's model without affecting amyloid levels.

The paper investigates how distinct hyperactive RAS/MAPK alleles affect cortical GABAergic interneurons, revealing shared molecular programs and a role for increased neural activity in altering interneuron subtypes.

This study investigates the role of ERK1/2 signaling in the development of MGE-derived glia and cortical inhibitory neurons, showing its necessity for glial number and activity-dependent responses in neurons.